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Clomid for Testosterone
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revenge Offline
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Post: #176
RE: Clomid for Testosterone
https://forums.t-nation.com/t/does-inhib.../222643/25
https://www.ncbi.nlm.nih.gov/pubmed/9759700

here the study and topic ı was talking about
kassad you should be also checking this
(This post was last modified: 08-08-2019 04:50 PM by revenge.)
08-08-2019 04:49 PM
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jbc09 Offline
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Post: #177
RE: Clomid for Testosterone
Me and other friend are using now exemestane 12,5 mg EOD + tongkat ali(5 days on 2 days off) since some weeks ago and the feeling is nothing incredible, I would like to make a blood test and let you know the results. About body results for the moment nothing special maybe a bit more vascular, but normally I have good vascular body. I am 35 years and want to boost the natural options. Never used roids.
I am thinking on Androtest(4-androstenediol) by fusion suplemments, this prohormone converts at 15% to testosterone, but really the good thing is the prohormone by it self(not the conversion) because 4-androstenediol is alredy androgenic and anabolic and less suppresive than testosterone because it doesnt bind well to androgen receptor and doesnt convert in estradiol. So the inhibition is very very low
Does anyone try it? I would like to know when should be the best moment to take the pills(6-8 per day) to minimize the shutdown. Maybe all of them in the morning..?
I would like to know if is less or more suppresive than primobolan
On the other hand read many good things about toremifene in this forum, for use during and before cycle, but is really really difficult to find where to buy it here
08-10-2019 10:25 AM
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perros Offline
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Post: #178
RE: Clomid for Testosterone
Going to take injections.
08-10-2019 08:55 PM
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kassad Offline
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Post: #179
RE: Clomid for Testosterone
(08-08-2019 04:49 PM)revenge Wrote:  https://forums.t-nation.com/t/does-inhib.../222643/25
https://www.ncbi.nlm.nih.gov/pubmed/9759700

here the study and topic ı was talking about
kassad you should be also checking this

Thanks for the forum link, nice catch! The OP seems to be doing really nice work. He is doing 3mg of exemestane e4d, plus experimenting with boron and finasteride without being on any form of exogenous testosterone. And he is achieving the exact same free test numbers as the 25mg and 50mg group in the exemestane study.
08-11-2019 02:06 PM
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jbc09 Offline
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Post: #180
RE: Clomid for Testosterone
3mg exemestane! Which is the amazing technology for cut this 25 mg micropills in 3 mg size..
08-14-2019 04:22 AM
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revenge Offline
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Post: #181
RE: Clomid for Testosterone
ı took 12.5mg eod as a trial without finasteride and ı guess crashed my e2 felt fatigued low energy was sleeping like 10+hours but still felt tired typical low e2 sides also got acne and lowered libido ıt was 12.5mg monday 6.5mg thursday will go 6.25mg 2x a week and in 2 days ı will be buying finasteride too it is a must to stack finasteride with aromasin because finasteride lowers dht thus increases shbg which will be countered by aromasin
08-14-2019 05:56 AM
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kassad Offline
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Post: #182
RE: Clomid for Testosterone
(08-14-2019 04:22 AM)jbc09 Wrote:  3mg exemestane! Which is the amazing technology for cut this 25 mg micropills in 3 mg size..

Research chems are usually dosed 25mg/ml. The first ticker on a standard 1ml syringe is 0.02ml which is 0.5mg of exemestane.
08-14-2019 08:40 AM
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kassad Offline
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Post: #183
RE: Clomid for Testosterone
There is a lot of misunderstanding about the exemestane dosing.

The 25mg/day dose came from using 1pill/day as pills are 25mg each.

Looking at the female breast cancer dose finding studies rangeing from 0.5mg to 25mg they measured the following three E1 (estrone), E2 (estradiol) and E1S (estrone-sulfate).

E2 suppression is already maximal at the dose of 5mg/day.
E1 suppression is maximal at 10mg/day and above.
E1S suppression is maximal at 25mg/day and above.

If you are combating breast cancer you need to suppress all three, so thatswhy the pills are dosed at 25mg.

If you are injecting testosterone and want to lower high E2 sides you only need to concentrate on E2 suppression. Which means you'll never need more than 5mg/day (if that isn't enough, more won't be either, you'll need a different compound, a stronger one like letrozole).

If you are using it to boost your own production however you'll have maximal LH boosting effect at 10mg because both E1 and E2 play a role on the feedback loop.

So here it is why finding the dose is hard:
You can't really feel low E1 sides, as it's a much weaker estrogen on ERa and ERb receptors than E2. But E2 is suppressed to the max (whatever that is for you, according to the 25mg exemestane male study: 32 ± 29% (mean +-SD)) at a lower dose of 5mg/day. Which might be too much for you already depending on your baseline E2 and depending on how strong your response is to the AIs. Again 32+-29, this means you have a 95% chance of anything between 3%-61% suppression of E2. This is why some people can take 25mg daily without issues (although they gain nothing above 10mg/day) and for others 5mg will be too much. If your E2 is in the low 20s and you suppress it by more than 30% you'll most likely doing too much.

And here it is why finding your dose becomes even harder:
The dose-effect relationship is non linear even below that 5mg max limit for E2 suppression. At 5mg you're at 100% of what is possible for you, but at 0.5mg you are already at 50% of what is possible. At 1mg you are at something like 70%, at 2.5mg at something like 85%.
And we haven't even discussed dosing eod or e2d or e3d. The above are when dosing daily...

So yeah, it is hard to find the correct dose. And you rarely see anyone starting from 0.5mg/day, but if you're one of those guys who have a maximal suppression reaction of say 50% and a baseline E2 in the 20s than 0.5mg/day would be about the maximum you should do as a monoteraphy based on the above...
08-14-2019 09:09 AM
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jbc09 Offline
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Post: #184
RE: Clomid for Testosterone
Very good explanación kassad, Many thanks
08-15-2019 12:39 PM
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