The explosion has caused widespread damage, with hospitals struggling to treat all the casualties.
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Lebanon's health minister has said at least 50 people have been killed and more than 2,700 were injured in the twin explosions in a set of televised remarks.
Lebanon security chief - blast caused by confiscated explosive materials
Lebanon's head of general security has reportedly said the blast was caused by confiscated explosive materials, including sodium nitrate, which was being kept near the port.
Sodium nitrate is primarily used as a preserving agent, but can also be used in pyrotechnics and smoke bombs.